Menu Close

At a Glance: Air Quality and Early Childhood Development

Learn key science takeaways and find actionable solutions to improve indoor air quality and support children’s health and well-being.

Published: September 9, 2025

At a Glance: Air Quality and Early Childhood Development.

Our At a Glance series tells you what you need to know about key topics in early childhood development and shares actionable strategies to support children’s health and well-being.  In this edition, learn how indoor air quality affects early childhood development—and find practical, actionable solutions that you can apply to support children and caregivers in your community. 


View References

  1. Klepeis NE, Nelson WC, Ott WR, et al. The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants. J Expo Anal Environ Epidemiol. 2001;11(3):231-252. doi:10.1038/sj.jea.7500165
  2. Nethery E, Brauer M, Janssen P. Time-activity patterns of pregnant women and changes during the course of pregnancy. J Expo Sci Environ Epidemiol. 2009;19(3):317-324. doi:10.1038/jes.2008.24
  3. US Environmental Protection Agency. How big a problem is poor indoor air quality (IAQ) in schools? US Environmental Protection Agency. https://www.epa.gov/iaq-schools/how-big-problem-poor-indoor-air-quality-iaq-schools
  4. US Environmental Protection Agency. Volatile organic compounds’ impact on indoor air quality. US Environmental Protection Agency. https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impact-indoor-air-quality
  5. Holden KA, Lee AR, Hawcutt DB, Sinha IP. The impact of poor housing and indoor air quality on respiratory health in children. Breathe (Sheff). 2023;19(2):230058. doi:10.1183/20734735.0058-2023
  6. Sen A, Heredia N, Senut MC, et al. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren. Sci Rep. 2015;5:14466. doi:10.1038/srep14466
  7. Goodrich AJ, Kleeman MJ, Tancredi DJ, et al. Pre-pregnancy ozone and ultrafine particulate matter exposure during second year of life associated with decreased cognitive and adaptive functioning at aged 2-5 years. Environ Res. 2024;252(Pt 1):118854. doi:10.1016/j.envres.2024.118854
  8. Zundel CG, Ryan P, Brokamp C, et al. Air pollution, depressive and anxiety disorders, and brain effects: a systematic review. Neurotoxicology. 2022;93:272-300. doi:10.1016/j.neuro.2022.10.011
  9. Young AS, Zoeller T, Hauser R, et al. Assessing indoor dust interference with human nuclear hormone receptors in cell-based luciferase reporter assays. Environ Health Perspect. 2021;129(4):047010. doi:10.1289/ehp8054
  10. Christensen GM, Marcus M, Naude PJW, et al. Joint effects of prenatal exposure to indoor air pollution and psychosocial factors on early life inflammation. Environ Res. 2024;252(Pt 1):118822.
  11. National Scientific Council on the Developing Child. Connecting the Brain to the Rest of the Body: Early Childhood Development and Lifelong Health Are Deeply Intertwined. Working Paper No. 15. National Scientific Council on the Developing Child; 2020. https://developingchild.harvard.edu
  12. Christensen GM, Marcus M, Naude PJW, et al. Joint effects of prenatal exposure to indoor air pollution and psychosocial factors on early life inflammation. Environ Res. 2024;252(Pt 1):118822. doi:10.1016/j.envres.2024.118822
  13. Evans J, Bansal A, Schoenaker D, Cherbuin N, Peek MJ, Davis DL. Birth outcomes, health, and health care needs of childbearing women following wildfire disasters: an integrative, state-of-the-science review. Environ Health Perspect. 2022;130(8):86001. doi:10.1289/EHP10544
  14. Rawat N, Kumar P. Interventions for improving indoor and outdoor air quality in and around schools. Sci Total Environ. 2023;858(Pt 2):159813. doi:10.1016/j.scitotenv.2022.159813

Download Resource:

Related Resource Guides