In 2011, a group of state-level policymakers in Washington State came together to answer one question: How could they improve outcomes for vulnerable young children and their families in Washington? Inspired and energized by the Center on the Developing Child’s integrated science of learning, behavior, and health, the policymakers coined the term “one science approach” to coordinate efforts across systems, policy, research, and practice. One result was the Washington Innovation Cluster, where the Center on the Developing Child’s Frontiers of Innovation (FOI) worked with local partners in Washington to build a strong infrastructure to support science-based innovation and a continuous flow of new ideas into the early childhood field.