Our approach to science-based innovation emphasizes the rapid design and testing of new intervention strategies grounded in the science of early childhood. This science helps us understand the factors that promote or derail healthy development, allowing us to develop interventions that use scientific concepts to address challenges facing young children. We embrace innovation as a “different way of working” that brings together researchers, practitioners, and community members in a fast-cycle process of co-creation in order to implement, test, and adapt these interventions.