Innovation clusters are cross-network collaborations between researchers, model developers, program sites, and practitioners. Within each cluster, project teams made up of researchers, developers, and site leaders co-design new strategies for addressing a specific unmet need within a population, such as increasing executive function skills in adult caregivers. The diverse pilot sites then test these strategies and share their findings across the innovation cluster to advance each other’s work and accelerate the overall rate of learning. For more on two innovation clusters in different stages of development, see the Brazilian Innovation Cluster, and the histories of the Latin American Innovation Clusters and the Washington Cluster.